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What Is Folding@home?

Started by TeaLeaf, September 05, 2003, 11:30:51 PM

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TeaLeaf

What is Folding@Home???
Folding@Home is a distributed computing project that is run by the Pandegroup at Stanford University. Their goal is to understand protein folding, protein aggregation, and related diseases.

What are proteins and why do they "fold"?
Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out their biochemical function, they assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, remains a mystery. Moreover, perhaps not surprisingly, when proteins do not fold correctly (i.e. "misfold"), there can be serious effects, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, and Parkinson's disease.  

For a protein to fold or misfold takes very little time, but it is hugely complicated. Analyses of the folding of even the simplest of proteins requires significant super computing power.  The amount of computing power required to perform these gargantuan calculations and to come up with any worthwhile results is massive and most supercomputers today would buckle under the pressure. This is where we come into the picture with the Folding@Home software.

What does the F@H software do?
The software will then run in the background.  It will try to download a set of data (a Work Unit - WU for short) from the Stanford University computers and then start processing the small amount of data.  When this work has been done it will send it back to Stanford and ask for more data upon which to work.  The WUs take a long time to complete even on the fastest home computers.  WUs may take hours and some WUs may take days, so please remember to pause the software first you need to reboot or shut shut down your machine, otherwise the work the you have completed on that WU will be lost and have to be re-started (edit by delanvital: work is now stored at for example 15 or 30 minute check points, you choose interval during installation. This basically means you can leave f@h to itself and you need not pay any special attention to f@h during your daily use of your PC).

You can download the installation package for the F@H program here.   Use the name checker at the bottom of this page to see if your preferred name is unique.

Make sure you enter 33597 (the Dead Men Folding team) as the team number.  In addition, it is recommended that you do not run the software in screensaver mode as this slows the speed at which your computer can process the work unit!

Will F@H make my PC run more slowly?
No it will not.  When your computer would otherwise be idle, the software grabs the surplus cpu cycles for the benefit of this research and processes some of the data.  When your computer needs to do some work for you the F@H program immediately stops.  The chances are that you you use only 10% of the processing power that is provided by your Pentium or Athlon powered computer. This means that 90% of the time that your PC is powered up your processor is doing absolutely nothing.  By running the Folding@Home software on your PC you can effectively use 100% of the processors capability as it only uses computing cycles that are unused.  You should not even notice that it is running. For example, you could run F@H and play CS simultaneously - you should not notice any difference in the speed of your machine!  If you want to make absolutely sure, then just adjust the option to limit the processor useage to 90%, thus always leaving 10% in reserve.

Deadmen Folding - Team 33597
In order to generate an additional element of interest in the F@H project, Stanford University allows teams to be set up who then compete to see who has managed to process the most WUs.  A completed WU (once received back by the university) is granted a certain number of points depending upon its complexity.    More completed WUs equals more points.  You can see who is in the Deadmen Folding team by looking here.   If you join the team (by downloading the software and entering your chosen name and our team number) you will automatically appear on our member's page when your first completed WU has been received.  

The Deadmen Folding team is open to anyone, so if you or a computer you know has some spare CPU time then please add it to our team folding effort!  Join the team and help us earn some more points!

Permission
Using other PCs to process more WUs and boost both your own and your teams total points score (aka Borging) is very popular.  However we do not wish to see anyone losing their job or being reprimanded over F@H.  So, if you wish to run the F@H software on machines that are not your own, please make sure that you have permission to do so!

TL.
TL.
Wisdom doesn\'t necessarily come with age. Sometimes age just shows up all by itself.  (Tom Wilson)
Talent wins games, but teamwork and intelligence wins championships. (Michael Jordan)

DuVeL

***BIG BUMP for all them SoG'gers...***
Survivor of LAN V, VI, VIII, IX, X, XII, XIV, XVI, XVIII, XX, XXIV, XXX, XXXII, XXXIV and XXXVI so far...
[QUOTE]Lionheart; Grolsch to DuVeL is like spinache to Popeye [/QUOTE]
[QUOTE]Cheesepuff...A cyborg is sent from the future on a deadly mission. He has to kill Ninja_Freak, a young Man whose life will have a great significance in years to come.Ninja has only one protector - DuVeL - also sent from the future. The Terminator uses his exceptional intelligence and strength to find Ninja_Freak & attempt to terminate him.
[/QUOTE]

Claw

F@H started now for team dMw :D :D


Neff

I downloaded it, and now i just executed the file, its "Benchmarking". How do i  type in the Team number? do i have to wait until its done benchmarking?
[quote=Adularena] Robin?!?!?! *shouts* "Lets ride, my nimble youngster!" - Mmmm, how batman loves Robin to hum the Batman theme (na nananan anan ananana BatMAN!!) while *cough* Exploring Batman`s secret grotto.[/quote]

TEH N00m IS BACK WITH TEH PWN!:yell:

Penfold

I think benchmarking is fine.

If you right click on the F@H icon by the clock and go to configure, yuou can put in your user name and theres a sport for the team number (33597 is dMw).

If you want to put ThePENDRAGON down as your user name then that too is fine :smile:

Any problems post back here and if I can't solve them there will be someone here who can.

Cheers

PEN

Penfold

Quote from: Claw;154932F@H started now for team dMw :D :D


:yahoo:  Nice one matey !

Now go recruit some more of your pixie friends to come and join in :biggrin:

PEN

Whitey

I look forward to posting your first milestone :biggrin:

Neff

Im now called "neffles" folding for me' homies!
[quote=Adularena] Robin?!?!?! *shouts* "Lets ride, my nimble youngster!" - Mmmm, how batman loves Robin to hum the Batman theme (na nananan anan ananana BatMAN!!) while *cough* Exploring Batman`s secret grotto.[/quote]

TEH N00m IS BACK WITH TEH PWN!:yell:

TeaLeaf

Quote from: Neff;155207Im now called "neffles" folding for me' homies!
Way to go Neff - welcome to the team!

TL.
TL.
Wisdom doesn\'t necessarily come with age. Sometimes age just shows up all by itself.  (Tom Wilson)
Talent wins games, but teamwork and intelligence wins championships. (Michael Jordan)

Jewelz^


Anonymous


Soulbringerx

Added my pc at work to it running 24/7 ;)
 
is it possible to run more pc's under 1 name?
Soulangel
Holypriest 20/41/0

enchanting 375
tailoring 375

Whitey

Quote from: Soulbringerx;177265Added my pc at work to it running 24/7 ;)
 
is it possible to run more pc's under 1 name?

Yes, the more the better :D

Thanks for your support (and Jewelz^).

DuVeL

Quote from: Soulbringerx;177265Added my pc at work to it running 24/7 ;)
 
is it possible to run more pc's under 1 name?

Yes!
All the computers where I have F@H on installed have the same username (I don't even remember how many computers).
If you install it on a workPC, make sure you ask your supervisor. Tell him it's for a good cause: It does research against Alzheimer and such.
For more info check:http://folding.stanford.edu/
Survivor of LAN V, VI, VIII, IX, X, XII, XIV, XVI, XVIII, XX, XXIV, XXX, XXXII, XXXIV and XXXVI so far...
[QUOTE]Lionheart; Grolsch to DuVeL is like spinache to Popeye [/QUOTE]
[QUOTE]Cheesepuff...A cyborg is sent from the future on a deadly mission. He has to kill Ninja_Freak, a young Man whose life will have a great significance in years to come.Ninja has only one protector - DuVeL - also sent from the future. The Terminator uses his exceptional intelligence and strength to find Ninja_Freak & attempt to terminate him.
[/QUOTE]

Soulbringerx

hehe i'm the supervisor :):taz:
Soulangel
Holypriest 20/41/0

enchanting 375
tailoring 375